Primary dysmenorrhea is a common condition that affects many women and can impair their quality of life. This study aims to compare the efficacy and safety of different non steroidal anti inflammatory drugs (NSAIDs) for relieving menstrual pain using a network meta analysis. The results may help clinicians and patients to choose the best option among various NSAIDs.
Introduction Back and neck pain are common musculoskeletal disorders. Topical non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to reduce pain and inflammation with fewer systemic side effects and drug interactions compared with oral NSAIDs. This study assessed efficacy and tolerability of a topical combination of capsaicin + diclofenac to treat acute back/neck pain. Methods
When compared with placebo, diclofenac provided consistently superior relief of symptoms. Comparisons with other nonsteroidal anti-inflammatory drugs or with opioids, such as pentazocine or Spasmofen, demonstrate that symptom relief with diclofenac was either comparable to or better than that obtained with these agents.
For example, naproxen/esomeprazole magnesium tablets were also found to be associated with significantly lower odds of gastric ulcers when compared with ibuprofen; gastroduodenal ulcers when compared with ibuprofen or diclofenac; dyspepsia when compared with naproxen, ibuprofen, diclofenac, etoricoxib, or fixed-dose diclofenac sodium plus
Taking the NSAID and Tylenol at the same time will give better superior pain relief than in scenario #1 but may wear off before it's time for the next dose in 4-6 hours. Alternating the two drugs, for example, the NSAID at 0,4, and 8 hours plus the Tylenol at 2,6, and 10 hours will produce a more sustained level of pain relief.
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is diclofenac better than naproxen